Some people believe that ME/CFS will always have a viral trigger. Collagen, Ligament Laxity, and the Most Common ME/CFS Triggers Whether this is accomplished by a fusion or by regenerative medicine, the goal is to relieve the mechanical stress on neural tissues.īut why would our joints fail, and our ligaments become lax, in the first place? There are multiple possibilities. Stabilizing the craniocervical junction can eliminate symptoms by preventing excess mobility. When the skull and upper spine move too much, as in cases of craniocervical instability (CCI), this can cause mechanical deformative stress on the brainstem. This is the most mobile portion of the spine. Without competent connective tissue, these joints can become unstable, failing to limit excess motion. The craniocervical junction relies in part on the connective tissue of ligaments and joints. Phair's question: In my own case, and in the case of some others with ME, the joints and ligaments of the craniocervical junction had become unable to hold in place the skull and upper cervical spine. “ Surely the absence of steel support is not the cause of the disease. In one conversation, a patient asked him why a fusion surgery would eliminate ME/CFS symptoms, as it did for me and now multiple others. He has chosen to directly engage with the online patient community on Phoenix Rising. Phair has been quite generous with his time. Let's dive in, below! A Public Conversationĭr. At the same time, they are not inconsistent or conflicting. The Mechanical Paradigm and the Metabolic Trap Hypothesis are very different ways of thinking about ME/CFS. The second most frequent question people ask me is: “ Jeff, how does the Mechanical Paradigm relate to the Metabolic Trap Hypothesis proposed by Dr. Secondly, out of those with ME that have had these conditions confirmed, some have been able to address the problem non-surgically, such as with regenerative medicine.
My hypothesis is that mechanical neurological conditions may be the underlying cause of many, but we need further research to confirm or disprove this. In short - not necessarily! First, we do not yet know exactly what percentage of people with ME have CCI or other underlying structural conditions.
Since proposing the Mechanical Paradigm, the number one question people have asked me is: “ Jeff, are you saying everyone with ME has CCI, and that everyone with ME will need neurosurgery?” My specific focus has been on craniocervical instability (CCI) and tethered cord syndrome as physical causes of ME/CFS. Other mechanical neurological conditions include intracranial hypertension, Chiari malformations, Eagle’s syndrome, and cervical stenosis. These mechanical concepts, involving neural injury in a setting of compromised connective tissue, may also be relevant to Long COVID. Mechanical conditions may be the cause of ME for a significant percentage of people – or possibly for the majority. Structural neurological conditions involving our connective tissue, such as craniocervical instability (CCI), could be one type of injury that can cause ME/CFS.
The injury can be triggered by a virus, an impact trauma, or other events. The idea is that ME happens as a result of a physical injury to our neural tissues. I also developed a novel hypothesis of the disease: The Mechanical Paradigm. In 2017, I solved my case of ME through my own research. I Developed the Mechanical Paradigm in 2018
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